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Volume 39 , Issue 1
January/February 2019
Pages 9–14

Evaluation of the Combination of Strip Gingival Grafts and a Xenogeneic Collagen Matrix for the Treatment of Severe Mucogingival Defects: A Human Histologic Study

Istvan A. Urban, DMD, MD/Katalin Nagy, DMD, PhD/Sabine Werner, PhD/Michael Meyer, PhD

PMID: 30543721
DOI: 10.11607/prd.3921

Predictable and effective surgical techniques that aim to increase the width of keratinized gingiva, relocate the mucogingival junction, and deepen the vestibule often involve soft tissue autografts; however, soft tissue autograft supply is limited and its harvesting is associated with patient morbidity. With a strip autograft and xenogeneic collagen matrix (XCM) technique combination, autograft harvest requirements and patient morbidity are reduced. In this histologic evaluation, 12 strip autograft/XCM biopsy samples were compared with 3 reference samples of palatal strip autografts. Tissue morphology, keratin, and collagen expression appear identical, indicating that the combined grafting technique provides desired and physiologically normal keratinized gingiva.

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